Chronic Inflammatory Response Syndrome is a multisymptom, multisystem illness usually acquired following respiratory exposure to water-damaged buildings.

  • It is an under-recognized, underdiagnosed dysregulation of the innate immune system that can affect 25% of the population, therefore representing a silent epidemic.

  • The only treatment in the published literature documenting clinical efficacy for the treatment of Chronic Inflammatory Response Syndrome is the Shoemaker Protocol.

  • Myalgic Encephalomyelitis/Chronic Fatigue Syndrome is a common misdiagnosis for Chronic Inflammatory Response Syndrome but lacks a defined etiology, biomarkers, or a treatment protocol that reverses the underlying conditions.

  • CIRS can be acquired from exposure to biotoxins including mold, actinobacteria, endotoxins, a tick bite, a recluse spider bite or exposure to water contaminated with toxins in an area with fish kills such as Pfiesteria or Cyanobacteria.

Reference NIH.gov and SurvivingMold.com